FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term histone H3K36 demethylase activity ID (Ontology) GO:0051864 (Gene Ontology)
Definition Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.[ PubMed:16362057 ]
Also Known As"[histone-H3]-lysine-36 demethylase activity" ; "histone demethylase activity (H3-K36 specific)" ; "histone H3-K36 demethylase activity" (for all, see Synonyms field below)
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 histone H3K36 demethylase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | histone H3K36 demethylase activity
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oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
 |__2-oxoglutarate-dependent dioxygenase activity__
histone demethylase activity                       |
 |__histone H3 demethylase activity________________|
dioxygenase activity                               |
 |__2-oxoglutarate-dependent dioxygenase activity__|
                                                   histone H3K36 demethylase activity  5 rec.
                                                    |__histone H3K36me/H3K36me2 demethylase activity
                                                    |__histone H3K36me2/H3K36me3 demethylase activity 2 rec.
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Is a 2-oxoglutarate-dependent dioxygenase activity
histone H3 demethylase activity
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Synonyms
  • "[histone-H3]-lysine-36 demethylase activity" EXACT
    "histone demethylase activity (H3-K36 specific)" EXACT
    "histone H3-K36 demethylase activity" EXACT
    "histone H3-lysine-36 demethylase activity" EXACT
    "histone H3-methyl-lysine-36 demethylase activity" EXACT
    "histone-lysine (H3-K36) demethylase activity" EXACT
    "histone-lysine demethylase activity (H3-K36 specific)" EXACT
    "histone-lysine(H3-K36) demethylase activity" EXACT
Secondary IDs
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