FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term G-quadruplex DNA binding ID (Ontology) GO:0051880 (Gene Ontology)
Definition Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.[ PubMed:16142245 PubMed:9512530 ]
Also Known As "G quadruplex DNA binding" ; "G quartet DNA binding" ; "G-DNA binding" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Genes
 G-quadruplex DNA binding (all annotations which use CV term, excluding "NOT" statements)       2
     enables | G-quadruplex DNA binding       2
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  nucleic acid binding
   |__DNA binding
       |__G-quadruplex DNA binding  2 rec.
           |__telomeric G-quadruplex DNA binding
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Synonyms
  • "G quadruplex DNA binding" EXACT
    "G quartet binding" BROAD
    "G quartet DNA binding" EXACT
    "G-DNA binding" EXACT
    "G-quartet binding" BROAD
    "G-quartet DNA binding" EXACT
    "quadruplex DNA binding" EXACT
    "tetraplex DNA binding" EXACT
Secondary IDs
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