FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term inositol-1,4,5-trisphosphate 5-phosphatase activity ID (Ontology) GO:0052658 (Gene Ontology)
Definition Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 inositol-1,4,5-trisphosphate 5-phosphatase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | inositol-1,4,5-trisphosphate 5-phosphatase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  inositol trisphosphate phosphatase activity
   |__inositol-polyphosphate 5-phosphatase activity
       |__inositol-1,4,5-trisphosphate 5-phosphatase activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a inositol-polyphosphate 5-phosphatase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity" RELATED[ EC:3 ]
    "5PTase activity" RELATED[ EC:3 ]
    "D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity" RELATED[ EC:3 ]
    "D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity" RELATED[ EC:3 ]
    "D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity" RELATED[ EC:3 ]
    "inosine triphosphatase activity" RELATED[ EC:3 ]
    "inositol 1,4,5-trisphosphate phosphatase activity" BROAD[ EC:3 ]
    "inositol phosphate 5-phosphomonoesterase activity" BROAD[ EC:3 ]
    "inositol polyphosphate-5-phosphatase activity" BROAD[ EC:3 ]
    "Ins(1,4,5)P3 5-phosphatase activity" RELATED[ EC:3 ]
    "InsP(3) 5-phosphatase activity" BROAD[ EC:3 ]
    "InsP3 5-phosphatase activity" BROAD[ EC:3 ]
    "L-myo-inositol 1,4,5-trisphosphate-monoesterase activity" BROAD[ EC:3 ]
    "myo-inositol-1,4,5-trisphosphate 5-phosphatase activity" RELATED[ EC:3 ]
    "type I inositol-polyphosphate phosphatase activity" RELATED[ EC:3 ]
    "type II inositol polyphosphate 5-phosphatase activity" RELATED
Secondary IDs
hide External Crossreferences & Linkouts
KEGG_REACTION:R03394
MetaCyc:3.1.3.56-RXN
Reactome:R-HSA-1855174 "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol"
Reactome:R-HSA-1855222 "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane"
RHEA:19797