FB2026_02 , released June 18, 2026

CV Term Report

Help Close All Open All

General Information

Term

class II DNA-(apurinic or apyrimidinic site) endonuclease activity

ID (Ontology)

GO:0052720 (Gene Ontology)

Definition

Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.[ PubMed:1698278 ]

Also Known As

"class II DNA-(apurinic or apyrimidinic site) lyase activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
class II DNA-(apurinic or apyrimidinic site) endonuclease activity (all annotations which use CV term, excluding "NOT" statements)
enables \| class II DNA-(apurinic or apyrimidinic site) endonuclease activity	--

Spanning Tree (Parents/Children)

DNA endonuclease activity
 |__DNA-(apurinic or apyrimidinic site) endonuclease activity__
 |__DNA endonuclease activity, producing 5'-phosphomonoesters__|
hydrolase activity, acting on ester bonds                      |
 |__DNA endonuclease activity, producing 5'-phosphomonoesters__|
                                                               class II DNA-(apurinic or apyrimidinic site) endonuclease activity  4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	DNA-(apurinic or apyrimidinic site) endonuclease activity DNA endonuclease activity, producing 5'-phosphomonoesters
Part of
Synonyms & Secondary IDs
Synonyms
	"class II AP endonuclease activity" RELATED "class II DNA-(apurinic or apyrimidinic site) lyase activity" EXACT
Secondary IDs

External Crossreferences & Linkouts