FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term N(1)-acetylpolyamine oxidase activity ID (Ontology) GO:0052903 (Gene Ontology)
Definition Catalysis of the reaction: N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2. Also converts N(1)-acetylspermidine to putrescine, and N(1),N(12)-diacetylspermine to N(1)-acetylspermidine.[ EC:1 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 N(1)-acetylpolyamine oxidase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | N(1)-acetylpolyamine oxidase activity       1
Spanning Tree (Parents/Children)
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  oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor
   |__polyamine oxidase activity
       |__N(1)-acetylpolyamine oxidase activity  1 rec.
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Is a polyamine oxidase activity
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Synonyms
  • "N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity" NARROW[ EC:1 ]
    "N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity" NARROW[ EC:1 ]
Secondary IDs
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EC:1.5.3.13
KEGG_REACTION:R03899
MetaCyc:RXN-10460
MetaCyc:RXN-12091
MetaCyc:RXN-9940
Reactome:R-HSA-141348 "PAO:FAD oxidises NASPM to PTCN"
Reactome:R-HSA-141351 "PAOX:FAD oxidises NASPN to SPM"
RHEA:25800
RHEA:25812
RHEA:25868