FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term large conductance calcium-activated potassium channel activity ID (Ontology) GO:0060072 (Gene Ontology)
Definition Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.[ ISBN:0815340729 PubMed:17115074 ]
Also Known As"BK calcium-activated potassium channel activity" ; "BK KCa channel activity" ; "large conductance KCa channel activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 large conductance calcium-activated potassium channel activity (all annotations which use CV term, excluding "NOT" statements)
     enables | large conductance calcium-activated potassium channel activity       --
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calcium-activated cation channel activity__
potassium channel activity_________________|
                                           calcium-activated potassium channel activity
                                            |__large conductance calcium-activated potassium channel activity  2 rec.
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  • "BK calcium-activated potassium channel activity" EXACT
    "BK channel activity" RELATED
    "BK KCa channel activity" EXACT
    "large conductance KCa channel activity" EXACT
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