FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term long-term synaptic depression ID (Ontology) GO:0060292 (Gene Ontology)
Definition A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
Also Known As"long term synaptic depression"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 long-term synaptic depression (all annotations which use CV term, excluding "NOT" statements)
     involved_in | long-term synaptic depression
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negative regulation of cell communication
 |__negative regulation of synaptic transmission__
negative regulation of signaling                  |
 |__negative regulation of synaptic transmission__|
modulation of chemical synaptic transmission      |
 |__regulation of synaptic plasticity_____________|
 |__negative regulation of synaptic transmission__|
regulation of biological quality                  |
 |__regulation of synaptic plasticity_____________|
                                                  long-term synaptic depression  1 rec.
                                                   |__regulation of long-term synaptic depression
                                                       |__negative regulation of long-term synaptic depression
                                                       |__positive regulation of long-term synaptic depression
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Is a regulation of synaptic plasticity
negative regulation of synaptic transmission
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Synonyms
  • "long term depression" BROAD
    "long term synaptic depression" EXACT
    "LTD" RELATED
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