FB2026_03 , released September 17, 2026
CV Term Report
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Term SMAD protein signal transduction ID (Ontology) GO:0060395 (Gene Ontology)
Definition An intracellular signaling cassette that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus and regulates transcription of specific target genes.
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 SMAD protein signal transduction (all annotations which use CV term, excluding "NOT" statements)
     involved_in | SMAD protein signal transduction
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enzyme-linked receptor protein signaling pathway
 |__cell surface receptor protein serine/threonine kinase signaling pathway__
intracellular signal transduction                                            |
 |__intracellular signaling cassette_________________________________________|
                                                                             SMAD protein signal transduction  11 rec.
                                                                              |__regulation of SMAD protein signal transduction 8 rec.
                                                                                  |__negative regulation of SMAD protein signal transduction 1 rec.
                                                                                  |__positive regulation of SMAD protein signal transduction 6 rec.
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Is a intracellular signaling cassette
Part of cell surface receptor protein serine/threonine kinase signaling pathway
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