FB2026_03 , released September 17, 2026
CV Term Report
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Term establishment of blood-brain barrier ID (Ontology) GO:0060856 (Gene Ontology)
Definition Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.[ PubMed:20080302 PubMed:30280653 ]
Also Known As"establishment of BBB" ; "establishment of blood/brain barrier"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 establishment of blood-brain barrier (all annotations which use CV term, excluding "NOT" statements)
     involved_in | establishment of blood-brain barrier
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nervous system development
 |__central nervous system development______________
cell differentiation                                |
 |__cell development________________________________|
system development                                  |
 |__central nervous system development______________|
anatomical structure development                    |
 |__cell development________________________________|
cellular developmental process                      |
 |__cell development________________________________|
animal gross anatomical part developmental process  |
 |__central nervous system development______________|
                                                    establishment of blood-brain barrier  23 rec.
                                                     |__establishment of endothelial blood-brain barrier
                                                     |__establishment of glial blood-brain barrier 17 rec.
                                                     |__regulation of establishment of blood-brain barrier 4 rec.
                                                         |__negative regulation of establishment of blood-brain barrier 1 rec.
                                                         |__positive regulation of establishment of blood-brain barrier
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Is a cell development
Part of central nervous system development
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Synonyms
  • "establishment of BBB" EXACT
    "establishment of blood/brain barrier" EXACT
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