FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term 2',3'-cyclic GMP-AMP synthase activity ID (Ontology) GO:0061501 (Gene Ontology)
Definition Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).[ PubMed:23258413 ]
Also Known As "2',3' cyclic GMP-AMP synthase activity" ; "2',3' cyclic-GMP-AMP synthase activity" ; "cyclic 2',3' GAMP synthase activity"
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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 2',3'-cyclic GMP-AMP synthase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 2',3'-cyclic GMP-AMP synthase activity
 NOT | enables | 2',3'-cyclic GMP-AMP synthase activity
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  nucleotidyltransferase activity
   |__cyclic GMP-AMP synthase activity
       |__2',3'-cyclic GMP-AMP synthase activity  2 rec.
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Is a cyclic GMP-AMP synthase activity
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Synonyms
  • "2',3' cyclic GMP-AMP synthase activity" EXACT
    "2',3' cyclic-GMP-AMP synthase activity" EXACT
    "cyclic 2',3' GAMP synthase activity" EXACT
    "cyclic-GMP-AMP synthase activity" BROAD
Secondary IDs
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EC:2.7.7.86
Reactome:R-HSA-3244614 "cGAS produces cyclic GMP-AMP"
RHEA:42064