FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

NEDD8 conjugating enzyme activity

ID (Ontology)

GO:0061654 (Gene Ontology)

Definition

Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
NEDD8 conjugating enzyme activity (all annotations which use CV term, excluding "NOT" statements)
enables \| NEDD8 conjugating enzyme activity

Spanning Tree (Parents/Children)

ubiquitin-like protein transferase activity
 |__NEDD8 transferase activity__________________________
 |__ubiquitin-like protein conjugating enzyme activity__|
                                                        NEDD8 conjugating enzyme activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	NEDD8 transferase activity ubiquitin-like protein conjugating enzyme activity
Part of
Synonyms & Secondary IDs
Synonyms
	"E2" BROAD
Secondary IDs

External Crossreferences & Linkouts
	EC:2.3.2.34