FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term SUMO ligase activity ID (Ontology) GO:0061665 (Gene Ontology)
Definition Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S = X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       7
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 SUMO ligase activity (all annotations which use CV term, excluding "NOT" statements)       7
     enables | SUMO ligase activity       7
Spanning Tree (Parents/Children)
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ubiquitin-like protein transferase activity
 |__SUMO transferase activity_______________
 |__ubiquitin-like protein ligase activity__|
                                            SUMO ligase activity  7 rec.
                                             |__SUMO-ubiquitin ligase activity
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Is a SUMO transferase activity
ubiquitin-like protein ligase activity
Part of
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Synonyms
  • "E3" BROAD
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-9834809 "SUMOylation of PKR"
Reactome:R-HSA-9842868 "TRIM28 in TRIM28:KRAB-ZFP:retroelement chromatin autoSUMOylates with SUMO2"