FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term protein-lysine-acetyltransferase activity ID (Ontology) GO:0061733 (Gene Ontology)
Definition Catalysis of the reaction: L-lysyl-[protein] + acetyl-CoA = N6-acetyl-L-lysyl-[protein] + CoA + H+.
Also Known As "peptide-lysine-acetyltransferase activity" ; "peptide-lysine-N-acetylase activity" ; "peptide-lysine-N-acetyltransferase activity" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein-lysine-acetyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein-lysine-acetyltransferase activity       --
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N-acetyltransferase activity________
protein N-acyltransferase activity__|
                                    protein N-acetyltransferase activity
                                     |__protein-lysine-acetyltransferase activity  29 rec.
                                         |__acetyl-CoA synthetase acetyltransferase activity
                                         |__histone acetyltransferase activity 21 rec.
                                         |   |__histone H1 acetyltransferase activity(+)
                                         |   |__histone H2A acetyltransferase activity(+) 2 rec.
                                         |   |__histone H2B acetyltransferase activity(+)
                                         |   |__histone H3 acetyltransferase activity(+) 6 rec.
                                         |   |__histone H4 acetyltransferase activity(+) 10 rec.
                                         |__tubulin N-acetyltransferase activity 3 rec.
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Is a protein N-acetyltransferase activity
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Synonyms
  • "peptide-lysine-acetyltransferase activity" EXACT
    "peptide-lysine-N-acetylase activity" EXACT
    "peptide-lysine-N-acetyltransferase activity" EXACT
    "protein acetylase activity" EXACT
    "protein acetyltransferase activity" EXACT
    "protein-lysine-N-acetylase activity" EXACT
Secondary IDs
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EC:2.3.1.48
Reactome:R-HSA-6811508 "ING2-bound EP300 acetylates TP53"
Reactome:R-HSA-8951966 "EP300 acetylates RUNX3"
Reactome:R-HSA-9617758 "EP300,CREBBP acetylate FOXO4"
Reactome:R-HSA-9620515 "KAT2B,EP300 acetylate FOXO3 under oxidative stress"
Reactome:R-HSA-9626945 "CREBBP acetylates FOXO1"
Reactome:R-HSA-9701531 "p-Y705,S727 STAT3 is acetylated"
Reactome:R-HSA-9756494 "CREBBP acetylates SARS-CoV-2 N at K375"
Reactome:R-HSA-9825747 "CREBBP acetylates HINT1 dimer"
Reactome:R-HSA-9920716 "CLOCK acetylates BMAL1 on lysine-538"
RHEA:45948
RHEA:74151