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| Term | type 2 mitophagy | ID (Ontology) | GO:0061734 (Gene Ontology) | |||||||
| Definition | The selective autophagy process in which a mitochondrion is degraded by macroautophagy in a process initiated by mitochondrial depolarization (mtDepo) followed by Parkin binding, and ubiquitination of outer membrane proteins, to remove potentially harm-inducing dysfunctional/damaged mitochondria.[ PubMed:25009776 PubMed:25349190 ] | |||||||||
| Also Known As | "Park2-mediated mitophagy in response to mitochondrial depolarization" ; "parkin-mediated mitophagy in response to mitochondrial depolarization" ; "PRKN-mediated mitophagy in response to mitochondrial depolarization" | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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autophagy of mitochondrion__ macroautophagy______________| mitophagy |__type 2 mitophagy 4 rec. |__regulation of type 2 mitophagy 2 rec. |__negative regulation of type 2 mitophagy 1 rec. |__positive regulation of type 2 mitophagy 1 rec. |
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| Is a | mitophagy | ||
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