FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term glutathione specific gamma-glutamylcyclotransferase activity ID (Ontology) GO:0061928 (Gene Ontology)
Definition Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine.[ PubMed:23070364 PubMed:27913623 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 glutathione specific gamma-glutamylcyclotransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | glutathione specific gamma-glutamylcyclotransferase activity
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  carbon-nitrogen lyase activity
   |__amidine-lyase activity
       |__glutathione specific gamma-glutamylcyclotransferase activity  2 rec.
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Is a amidine-lyase activity
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EC:4.3.2.7
Reactome:R-HSA-6785928 "CHAC1,2 cleaves GSH to OPRO and CysGly"
RHEA:47724