FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term peptidyl-aspartic acid 3-dioxygenase activity ID (Ontology) GO:0062101 (Gene Ontology)
Definition Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.[ PubMed:1378441 PubMed:1856229 ]
Also Known As "peptide-aspartate beta-dioxygenase activity"
Comment
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 peptidyl-aspartic acid 3-dioxygenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | peptidyl-aspartic acid 3-dioxygenase activity       1
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catalytic activity
 |__catalytic activity, acting on a protein____________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen  |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
dioxygenase activity                                                                                   |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
                                                                                         peptidyl-aspartic acid 3-dioxygenase activity  1 rec.
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Is a 2-oxoglutarate-dependent dioxygenase activity
catalytic activity, acting on a protein
Part of
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Synonyms
  • "aspartate beta-hydroxylase activity" RELATED[ EC:1 ]
    "aspartyl/asparaginyl beta-hydroxylase activity" RELATED[ EC:1 ]
    "aspartylpeptide beta-dioxygenase activity" RELATED[ EC:1 ]
    "peptide-aspartate beta-dioxygenase activity" EXACT
    "peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.14.11.16
MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN
Reactome:R-HSA-9631355 "ASPH:Fe2+ hydroxylates an aspartate residue of F9"
RHEA:11508