FB2026_03 , released September 17, 2026
CV Term Report
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Term ubiquitin-dependent endocytosis ID (Ontology) GO:0070086 (Gene Ontology)
Definition Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.[ PubMed:9409540 ]
Also Known As"ubiquitin-mediated endocytosis"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 ubiquitin-dependent endocytosis (all annotations which use CV term, excluding "NOT" statements)
     involved_in | ubiquitin-dependent endocytosis
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transport
 |__protein transport___________________________________
intracellular protein localization                      |
 |__protein transport___________________________________|
 |__protein localization to organelle___________________|
establishment of protein localization                   |
 |__protein transport___________________________________|
 |__establishment of protein localization to organelle__|
import into cell                                        |
 |__endocytosis_________________________________________|
                                                        ubiquitin-dependent endocytosis  3 rec.
                                                         |__regulation of ubiquitin-dependent endocytosis 1 rec.
                                                             |__negative regulation of ubiquitin-dependent endocytosis
                                                             |__positive regulation of ubiquitin-dependent endocytosis 1 rec.
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Is a endocytosis
protein transport
protein localization to organelle
establishment of protein localization to organelle
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  • "ubiquitin-mediated endocytosis" EXACT
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