FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

5'-tyrosyl-DNA phosphodiesterase activity

ID (Ontology)

GO:0070260 (Gene Ontology)

Definition

Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.[ PubMed:16751265 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
5'-tyrosyl-DNA phosphodiesterase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| 5'-tyrosyl-DNA phosphodiesterase activity

Spanning Tree (Parents/Children)

phosphoric diester hydrolase activity__
catalytic activity, acting on DNA______|
                                       tyrosyl-DNA phosphodiesterase activity
                                        |__5'-tyrosyl-DNA phosphodiesterase activity  1 rec.

Spanning Tree View Settings
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Relationships
Is a	tyrosyl-DNA phosphodiesterase activity
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts