FB2026_03 , released September 17, 2026
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Term negative regulation of ERK1 and ERK2 cascade ID (Ontology) GO:0070373 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.[ ISBN:0121245462 ISBN:0896039986 ]
Also Known As"down regulation of ERK1 and ERK2 cascade" ; "down-regulation of ERK1 and ERK2 cascade" ; "downregulation of ERK1 and ERK2 cascade" (for all, see Synonyms field below)
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 negative regulation of ERK1 and ERK2 cascade (all annotations which use CV term, excluding "NOT" statements)
     involved_in | negative regulation of ERK1 and ERK2 cascade
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regulation of MAPK cascade
 |__negative regulation of MAPK cascade___________________
 |__regulation of ERK1 and ERK2 cascade___________________|
ERK1 and ERK2 cascade                                     |
 |__regulation of ERK1 and ERK2 cascade___________________|
negative regulation of intracellular signal transduction  |
 |__negative regulation of MAPK cascade___________________|
                                                          negative regulation of ERK1 and ERK2 cascade  23 rec.
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Is a negative regulation of MAPK cascade
regulation of ERK1 and ERK2 cascade
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Synonyms
  • "down regulation of ERK1 and ERK2 cascade" EXACT
    "down-regulation of ERK1 and ERK2 cascade" EXACT
    "downregulation of ERK1 and ERK2 cascade" EXACT
    "inhibition of ERK1 and ERK2 cascade" NARROW
    "negative regulation of ERK cascade" BROAD
    "negative regulation of ERK1 and ERK2 signaling pathway" EXACT
    "negative regulation of ERK1 and ERK2 signalling pathway" EXACT
    "negative regulation of ERK1 cascade" NARROW
    "negative regulation of ERK1/2 cascade" EXACT
    "negative regulation of ERK2 cascade" NARROW
    "negative regulation of MAPK1 cascade" NARROW
    "negative regulation of MAPK3 cascade" NARROW
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