FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term death domain binding ID (Ontology) GO:0070513 (Gene Ontology)
Definition Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 death domain binding (all annotations which use CV term, excluding "NOT" statements)
     enables | death domain binding
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  protein binding
   |__protein domain specific binding
       |__death domain binding  2 rec.
           |__BH3 domain binding
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