FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

metallodipeptidase activity

ID (Ontology)

GO:0070573 (Gene Ontology)

Definition

Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Also Known As

"metallo-exo-dipeptidase activity" ; "metalloexodipeptidase activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
metallodipeptidase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| metallodipeptidase activity	--

Spanning Tree (Parents/Children)

metallopeptidase activity
 |__metalloexopeptidase activity__
exopeptidase activity             |
 |__metalloexopeptidase activity__|
 |__dipeptidase activity__________|
                                  metallodipeptidase activity  5 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	metalloexopeptidase activity dipeptidase activity
Part of
Synonyms & Secondary IDs
Synonyms
	"metallo-exo-dipeptidase activity" EXACT "metalloexodipeptidase activity" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-2022398 "ACE:Zn2+ hydrolyzes AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7))" Reactome:R-HSA-2022405 "ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))" Reactome:R-HSA-2065355 "Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8))"