FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity ID (Ontology) GO:0070626 (Gene Ontology)
Definition Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (all annotations which use CV term, excluding "NOT" statements)
     enables | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity
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  carbon-nitrogen lyase activity
   |__amidine-lyase activity
       |__(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity  1 rec.
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Is a amidine-lyase activity
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Synonyms
  • "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity" RELATED
    "adenylosuccinase activity" BROAD[ EC:4 ]
    "adenylosuccinate lyase activity" BROAD
    "SAICAR-lyase (fumarate forming) activity" RELATED
    "succino AMP-lyase activity" BROAD[ EC:4 ]
Secondary IDs
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KEGG_REACTION:R04559
MetaCyc:AICARSYN-RXN
Reactome:R-HSA-73800 "SAICAR => AICAR + Fumarate"
Reactome:R-HSA-73828 "adenylosuccinate => adenosine 5'-monophosphate + fumarate"
RHEA:23920