FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term macropinocytic cup ID (Ontology) GO:0070685 (Gene Ontology)
Definition A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.[ PubMed:12538772 PubMed:16968738 PubMed:9044041 ]
Also Known As "crown"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 macropinocytic cup (all annotations which use CV term, excluding "NOT" statements)
     is_active_in | macropinocytic cup
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  cell projection
   |__plasma membrane bounded cell projection
       |__macropinocytic cup  1 rec.
           |__macropinocytic cup cytoskeleton
           |__macropinocytic cup membrane
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Is a plasma membrane bounded cell projection
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