FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

PAS complex

ID (Ontology)

GO:0070772 (Gene Ontology)

Definition

A phosphatidylinositol kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKFYVE in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.[ PubMed:18950639 PubMed:19037259 PubMed:19158662 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
PAS complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| PAS complex

Spanning Tree (Parents/Children)

vacuole
 |__vacuolar membrane_______________________________________________
membrane                                                            |
 |__membrane protein complex________________________________________|
protein-containing complex                                          |
 |__membrane protein complex________________________________________|
bounding membrane of organelle                                      |
 |__vacuolar membrane_______________________________________________|
transferase complex                                                 |
 |__transferase complex, transferring phosphorus-containing groups__|
                                                                    PAS complex  3 rec.

Spanning Tree View Settings
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Relationships
Is a	transferase complex, transferring phosphorus-containing groups membrane protein complex
Part of	vacuolar membrane
Synonyms & Secondary IDs
Synonyms
	"autophagy-specific phosphatidylinositol 3-kinase complex" RELATED[ PubMed:24165940 ]
Secondary IDs

External Crossreferences & Linkouts