FB2026_03 , released September 17, 2026
CV Term Report
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Term phosphatidylserine exposure on apoptotic cell surface ID (Ontology) GO:0070782 (Gene Ontology)
Definition A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.[ PubMed:11536005 ]
Also Known As"externalization of phosphatidylserine"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 phosphatidylserine exposure on apoptotic cell surface (all annotations which use CV term, excluding "NOT" statements)
     involved_in | phosphatidylserine exposure on apoptotic cell surface
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apoptotic process
 |__execution phase of apoptosis_____________
plasma membrane organization                 |
 |__plasma membrane phospholipid scrambling__|
cellular process                             |
 |__execution phase of apoptosis_____________|
phospholipid translocation                   |
 |__plasma membrane phospholipid scrambling__|
                                             phosphatidylserine exposure on apoptotic cell surface  2 rec.
                                              |__regulation of phosphatidylserine exposure on apoptotic cell surface
                                                  |__negative regulation of phosphatidylserine exposure on apoptotic cell surface
                                                  |__positive regulation of phosphatidylserine exposure on apoptotic cell surface
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Is a plasma membrane phospholipid scrambling
Part of execution phase of apoptosis
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  • "externalization of phosphatidylserine" EXACT
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