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| Term | error-free translesion synthesis | ID (Ontology) | GO:0070987 (Gene Ontology) | |||||||
| Definition | The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level. | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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DNA damage tolerance_______________________ DNA synthesis involved in DNA replication__| translesion synthesis |__error-free translesion synthesis 2 rec. |
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| Is a | translesion synthesis | ||
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External Crossreferences & Linkouts
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| Reactome:R-HSA-110320 "Translesion Synthesis by POLH" | |||
