FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term medium-chain fatty acyl-CoA dehydrogenase activity ID (Ontology) GO:0070991 (Gene Ontology)
Definition Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = a medium-chain trans-(2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
Also Known As"MCAD activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 medium-chain fatty acyl-CoA dehydrogenase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | medium-chain fatty acyl-CoA dehydrogenase activity
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  oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
   |__acyl-CoA dehydrogenase activity
       |__medium-chain fatty acyl-CoA dehydrogenase activity  2 rec.
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Is a acyl-CoA dehydrogenase activity
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Synonyms
  • "MCAD activity" EXACT
Secondary IDs
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EC:1.3.8.7
MetaCyc:RXN-11734
RHEA:14477
RHEA:43464
RHEA:47296
RHEA:48176
RHEA:48180
RHEA:48208
RHEA:82951
RHEA:84471
RHEA:84475
RHEA:84607
RHEA:84611
RHEA:84615