FB2026_03 , released September 17, 2026
CV Term Report
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Term U2-type catalytic step 1 spliceosome ID (Ontology) GO:0071006 (Gene Ontology)
Definition A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.[ ISBN:0879695897 ISBN:0879697393 PubMed:18322460 PubMed:19239890 ]
Also Known As"major catalytic step 1 spliceosome" ; "U2-type activated spliceosome"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 U2-type catalytic step 1 spliceosome (all annotations which use CV term, excluding "NOT" statements)
     part_of | U2-type catalytic step 1 spliceosome
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spliceosomal complex
 |__U2-type spliceosomal complex__
 |__catalytic step 1 spliceosome__|
catalytic complex                 |
 |__catalytic step 1 spliceosome__|
                                  U2-type catalytic step 1 spliceosome  3 rec.
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Is a U2-type spliceosomal complex
catalytic step 1 spliceosome
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Synonyms
  • "GT-AG catalytic step 1 spliceosome" NARROW
    "major catalytic step 1 spliceosome" EXACT
    "mammalian U2-type spliceosomal complex B*" NARROW[ ISBN:0879695897 ISBN:0879697393 PubMed:19239890 ]
    "mammalian U2-type spliceosomal complex B2" NARROW[ ISBN:0879695897 ISBN:0879697393 ]
    "U2-type activated spliceosome" EXACT[ ISBN:0879695897 ISBN:0879697393 ]
    "yeast U2-type spliceosomal complex A1" NARROW[ ISBN:0879695897 ISBN:0879697393 ]
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