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General Information
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| Term |
14-3-3 protein binding |
ID (Ontology) |
GO:0071889 (Gene Ontology) |
| Definition |
Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.[ PubMed:15167810 PubMed:19575580 ] |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_MOLECULAR_FUNCTION | 3 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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14-3-3 protein binding (all annotations which use CV term, excluding "NOT" statements) | 3 | enables | 14-3-3 protein binding | 3 |
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Relationships
