FB2026_03 , released September 17, 2026
CV Term Report
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Term DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity ID (Ontology) GO:0072587 (Gene Ontology)
Definition Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity (all annotations which use CV term, excluding "NOT" statements)
     enables | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity
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enzyme regulator activity
 |__enzyme activator activity__________________________________________________________
 |__DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity__|
molecular function activator activity                                                  |
 |__ATPase activator activity__________________________________________________________|
 |__enzyme activator activity__________________________________________________________|
                                                                                       DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity  1 rec.
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Is a ATPase activator activity
enzyme activator activity
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
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