FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term Cul4-RING E3 ubiquitin ligase complex ID (Ontology) GO:0080008 (Gene Ontology)
Definition A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.[ PubMed:16792691 PubMed:18223036 PubMed:18552200 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
Genes (FBgn)GO_CELLULAR_COMPONENT
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 Cul4-RING E3 ubiquitin ligase complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | Cul4-RING E3 ubiquitin ligase complex
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  ubiquitin ligase complex
   |__cullin-RING ubiquitin ligase complex
       |__Cul4-RING E3 ubiquitin ligase complex  15 rec.
           |__CLRC complex
           |__Cul4A-RING E3 ubiquitin ligase complex 1 rec.
           |__Cul4B-RING E3 ubiquitin ligase complex
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Is a cullin-RING ubiquitin ligase complex
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