FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term fatty acid 2-hydroxylase activity ID (Ontology) GO:0080132 (Gene Ontology)
Definition Catalysis of the hydroxylation of the C-2 position in a fatty acid. The 2-hydroxylation may occur on free fatty acids or within the fatty acyl chain of a sphingolipid.[ PubMed:36902339 ]
Also Known As "fatty acid alpha-hydroxylase activity"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 fatty acid 2-hydroxylase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | fatty acid 2-hydroxylase activity       1
Spanning Tree (Parents/Children)
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monooxygenase activity_________________________________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen__|
                                                                                         oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
                                                                                          |__fatty acid 2-hydroxylase activity  1 rec.
                                                                                              |__4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity 1 rec.
                                                                                              |__dihydroceramide fatty acyl 2-hydroxylase activity
                                                                                              |__free fatty acid 2-hydroxylase activity 1 rec.
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Is a oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
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Synonyms
  • "fatty acid alpha-hydroxylase activity" EXACT
Secondary IDs
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Reactome:R-HSA-5693761 "FA2H hydroxylates 1,2-saturated fatty acids"