FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

negative regulation of release of cytochrome c from mitochondria

ID (Ontology)

GO:0090201 (Gene Ontology)

Definition

Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
negative regulation of release of cytochrome c from mitochondria (all annotations which use CV term, excluding "NOT" statements)
involved_in \| negative regulation of release of cytochrome c from mitochondria

Spanning Tree (Parents/Children)

release of cytochrome c from mitochondria
 |__regulation of release of cytochrome c from mitochondria__
negative regulation of signal transduction                   |
 |__negative regulation of apoptotic signaling pathway_______|
regulation of mitochondrion organization                     |
 |__regulation of release of cytochrome c from mitochondria__|
regulation of organelle organization                         |
 |__negative regulation of organelle organization____________|
negative regulation of apoptotic process                     |
 |__negative regulation of apoptotic signaling pathway_______|
negative regulation of cellular component organization       |
 |__negative regulation of organelle organization____________|
regulation of apoptotic signaling pathway                    |
 |__negative regulation of apoptotic signaling pathway_______|
                                                             negative regulation of release of cytochrome c from mitochondria  2 rec.

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Relationships
Is a	negative regulation of organelle organization regulation of release of cytochrome c from mitochondria negative regulation of apoptotic signaling pathway
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Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts