FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term 2-(3-amino-3-carboxypropyl)histidine synthase activity ID (Ontology) GO:0090560 (Gene Ontology)
Definition Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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Relevant FlyBase reports
 Gene Groups Genes
 2-(3-amino-3-carboxypropyl)histidine synthase activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | 2-(3-amino-3-carboxypropyl)histidine synthase activity       --       2
Spanning Tree (Parents/Children)
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  transferase activity
   |__transferase activity, transferring alkyl or aryl (other than methyl) groups
       |__2-(3-amino-3-carboxypropyl)histidine synthase activity  3 rec.
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Is a transferase activity, transferring alkyl or aryl (other than methyl) groups
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EC:2.5.1.108
MetaCyc:RXN-11371
Reactome:R-HSA-5358494 "DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2"
RHEA:36783