FB2026_03 , released September 17, 2026
CV Term Report
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Term t-circle formation ID (Ontology) GO:0090656 (Gene Ontology)
Definition A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).[ PubMed:19214183 PubMed:19581589 PubMed:19809492 PubMed:19858100 ]
Also Known As"telomeric circle formation"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 t-circle formation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | t-circle formation
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telomere maintenance
 |__telomere maintenance via telomere trimming__
DNA metabolic process                           |
 |__formation of extrachromosomal circular DNA__|
cellular component assembly                     |
 |__formation of extrachromosomal circular DNA__|
                                                t-circle formation  2 rec.
                                                 |__regulation of t-circle formation 1 rec.
                                                     |__negative regulation of t-circle formation 1 rec.
                                                     |__positive regulation of t-circle formation
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Is a formation of extrachromosomal circular DNA
Part of telomere maintenance via telomere trimming
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Synonyms
  • "telomeric circle formation" EXACT
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