FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

Bcl-2 family protein complex

ID (Ontology)

GO:0097136 (Gene Ontology)

Definition

A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.[ PubMed:14634621 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
Bcl-2 family protein complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| Bcl-2 family protein complex

Spanning Tree (Parents/Children)

  cellular_component
   |__protein-containing complex
       |__Bcl-2 family protein complex  3 rec.
           |__BAD-BCL-2 complex
           |__BAD-BCL-xl complex
           |__BAK complex
           |__BAX complex
           |__BCL-2 complex
           |__BID-BCL-2 complex
           |__BIM-BCL-2 complex
           |__BIM-BCL-xl complex
           |__NOXA-BCL-2 complex
           |__NOXA-BCL-xl complex
           |__PUMA-BCL-2 complex
           |__PUMA-BCL-xl complex

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	protein-containing complex
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts