FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term mitochondrial outer membrane permeabilization ID (Ontology) GO:0097345 (Gene Ontology)
Definition The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.[ PubMed:21041309 ]
Also Known As "mitochondrion outer membrane permeabilization" ; "MOMP"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Full annotation statements 
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 Genes
 mitochondrial outer membrane permeabilization (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | mitochondrial outer membrane permeabilization       1
Spanning Tree (Parents/Children)
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apoptotic process
 |__apoptotic signaling pathway_______________________________________________________________
signal transduction                                                                           |
 |__apoptotic signaling pathway_______________________________________________________________|
regulation of mitochondrial membrane permeability involved in apoptotic process               |
 |__positive regulation of mitochondrial membrane permeability involved in apoptotic process__|
mitochondrial outer membrane permeabilization involved in programmed cell death               |
                                                                                         mitochondrial outer membrane permeabilization  2 rec.
                                                                                         mitochondrial outer membrane permeabilization involved in programmed cell death(+) 2 rec.
                                                                                          |__positive regulation of mitochondrial membrane permeability involved in apoptotic process(+) 2 rec.
                                                                                          |   |__mitochondrial outer membrane permeabilization  2 rec.
                                                                                          |__regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 rec.
                                                                                              |__negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 rec.
                                                                                              |__positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
                                                                                                  |__regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 rec.
                                                                                                      |__negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 rec.
                                                                                                      |__positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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Is a positive regulation of mitochondrial membrane permeability involved in apoptotic process
Part of apoptotic signaling pathway
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Synonyms
  • "mitochondrial outer membrane permeabilization during apoptotic cell death" BROAD
    "mitochondrion outer membrane permeabilization" EXACT
    "MOMP" EXACT
Secondary IDs
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