FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

mitochondrial outer membrane permeabilization

ID (Ontology)

GO:0097345 (Gene Ontology)

Definition

The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.[ PubMed:21041309 ]

Also Known As

"mitochondrion outer membrane permeabilization" ; "MOMP"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
mitochondrial outer membrane permeabilization (all annotations which use CV term, excluding "NOT" statements)
involved_in \| mitochondrial outer membrane permeabilization

Spanning Tree (Parents/Children)

apoptotic process
 |__apoptotic signaling pathway_______________________________________________________________
signal transduction                                                                           |
 |__apoptotic signaling pathway_______________________________________________________________|
regulation of mitochondrial membrane permeability involved in apoptotic process               |
 |__positive regulation of mitochondrial membrane permeability involved in apoptotic process__|
mitochondrial outer membrane permeabilization involved in programmed cell death               |
 |__positive regulation of mitochondrial membrane permeability involved in apoptotic process__|
                                                                                         mitochondrial outer membrane permeabilization  2 rec.
                                                                                          |__regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 rec.
                                                                                              |__negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 rec.
                                                                                              |__positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	positive regulation of mitochondrial membrane permeability involved in apoptotic process
Part of	apoptotic signaling pathway
Synonyms & Secondary IDs
Synonyms
	"mitochondrial outer membrane permeabilization during apoptotic cell death" BROAD "mitochondrion outer membrane permeabilization" EXACT "MOMP" EXACT
Secondary IDs

External Crossreferences & Linkouts