FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein O-acetylglucosaminyltransferase activity ID (Ontology) GO:0097363 (Gene Ontology)
Definition Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.[ PubMed:22158438 ]
Also Known As"O-GlcNAc transferase" ; "O-linked N-acetylglucosaminyltransferase" ; "OGTase" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Gene Groups Genes
 protein O-acetylglucosaminyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein O-acetylglucosaminyltransferase activity       --
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catalytic activity
 |__catalytic activity, acting on a protein__
UDP-glycosyltransferase activity             |
 |__acetylglucosaminyltransferase activity___|
hexosyltransferase activity                  |
 |__acetylglucosaminyltransferase activity___|
                                             protein O-acetylglucosaminyltransferase activity  3 rec.
                                              |__RNA polymerase II C-terminal domain O-GlcNAc transferase activity
                                                  |__RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity
                                                  |__RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity
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Is a acetylglucosaminyltransferase activity
catalytic activity, acting on a protein
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Synonyms
  • "O-GlcNAc transferase" EXACT
    "O-linked N-acetylglucosaminyltransferase" EXACT
    "OGTase" EXACT
    "protein O-GlcNAc transferase activity" EXACT
    "UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase" EXACT
Secondary IDs
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EC:2.4.1.255
Reactome:R-HSA-8879117 "POMGNT2 transfers GlcNAc to Man-DAG1"
Reactome:R-HSA-9687828 "O-GlcNAcylation of RIPK3 (TLR4 signaling)"
RHEA:48904
RHEA:48908