FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

Gemini of Cajal bodies

ID (Ontology)

GO:0097504 (Gene Ontology)

Definition

Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA).[ PubMed:11031238 PubMed:9683623 ]

Also Known As

"Gemini of coiled bodies" ; "Gems"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
Gemini of Cajal bodies (all annotations which use CV term, excluding "NOT" statements)
located_in \| Gemini of Cajal bodies

Spanning Tree (Parents/Children)

nucleoplasm___________________________
intracellular membraneless organelle__|
                                      nuclear body
                                       |__Gemini of Cajal bodies  2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	nuclear body
Part of
Synonyms & Secondary IDs
Synonyms
	"Gemini of coiled bodies" EXACT "Gems" EXACT
Secondary IDs

External Crossreferences & Linkouts