FB2026_03 , released September 17, 2026
CV Term Report
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Term double-strand break repair via alternative nonhomologous end joining ID (Ontology) GO:0097681 (Gene Ontology)
Definition An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.[ PubMed:18584027 PubMed:21655080 ]
Also Known As"double-strand break repair via microhomology-mediated end joining"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 double-strand break repair via alternative nonhomologous end joining (all annotations which use CV term, excluding "NOT" statements)
     involved_in | double-strand break repair via alternative nonhomologous end joining
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  double-strand break repair
   |__double-strand break repair via nonhomologous end joining
       |__double-strand break repair via alternative nonhomologous end joining  2 rec.
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Is a double-strand break repair via nonhomologous end joining
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Synonyms
  • "A-NHEJ" RELATED
    "alt-NHEJ" RELATED
    "double-strand break repair via microhomology-mediated end joining" EXACT
    "MMEJ" RELATED
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