FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

cell surface receptor signaling pathway via STAT

ID (Ontology)

GO:0097696 (Gene Ontology)

Definition

An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.[ PubMed:21534947 PubMed:24587195 ]

Also Known As

"kinase activated-STAT cascade" ; "kinase-STAT cascade" ; "receptor signaling pathway via STAT" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
cell surface receptor signaling pathway via STAT (all annotations which use CV term, excluding "NOT" statements)
involved_in \| cell surface receptor signaling pathway via STAT

Spanning Tree (Parents/Children)

  signal transduction
   |__cell surface receptor signaling pathway
       |__cell surface receptor signaling pathway via STAT  47 rec.
           |__cell surface receptor signaling pathway via JAK-STAT 46 rec.
           |   |__regulation of receptor signaling pathway via JAK-STAT(+) 38 rec.
           |   |__tyrosine phosphorylation of STAT protein(+)
           |__regulation of receptor signaling pathway via STAT 39 rec.
               |__negative regulation of receptor signaling pathway via STAT(+) 21 rec.
               |__positive regulation of receptor signaling pathway via STAT(+) 18 rec.
               |__regulation of receptor signaling pathway via JAK-STAT(+) 38 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cell surface receptor signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"kinase activated-STAT cascade" EXACT "kinase-STAT cascade" EXACT "receptor signaling pathway via STAT" EXACT "STAT signalling pathway" EXACT
Secondary IDs

External Crossreferences & Linkouts