FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term cell surface receptor signaling pathway via STAT ID (Ontology) GO:0097696 (Gene Ontology)
Definition An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.[ PubMed:21534947 PubMed:24587195 ]
Also Known As "kinase activated-STAT cascade" ; "kinase-STAT cascade" ; "receptor signaling pathway via STAT" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Genes
 cell surface receptor signaling pathway via STAT (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | cell surface receptor signaling pathway via STAT       1
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  signal transduction
   |__cell surface receptor signaling pathway
       |__cell surface receptor signaling pathway via STAT  46 rec.
           |__cell surface receptor signaling pathway via JAK-STAT 45 rec.
           |   |__regulation of receptor signaling pathway via JAK-STAT(+) 37 rec.
           |   |__tyrosine phosphorylation of STAT protein(+)
           |__regulation of receptor signaling pathway via STAT 38 rec.
               |__negative regulation of receptor signaling pathway via STAT(+) 21 rec.
               |__positive regulation of receptor signaling pathway via STAT(+) 17 rec.
               |__regulation of receptor signaling pathway via JAK-STAT(+) 37 rec.
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Is a cell surface receptor signaling pathway
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Synonyms
  • "kinase activated-STAT cascade" EXACT
    "kinase-STAT cascade" EXACT
    "receptor signaling pathway via STAT" EXACT
    "STAT signalling pathway" EXACT
Secondary IDs
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