FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term O-phosphoseryl-tRNA(Sec) selenium transferase activity ID (Ontology) GO:0098621 (Gene Ontology)
Definition Catalysis of the reaction: O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate.[ PubMed:17142313 PubMed:19608919 ]
Also Known As"O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase" ; "O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase" ; "phosphoseryl-selenocysteinyl-tRNA selenium transferase activity" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 O-phosphoseryl-tRNA(Sec) selenium transferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | O-phosphoseryl-tRNA(Sec) selenium transferase activity
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transferase activity
 |__selenotransferase activity____________
catalytic activity, acting on RNA         |
 |__catalytic activity, acting on a tRNA__|
                                          O-phosphoseryl-tRNA(Sec) selenium transferase activity  1 rec.
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Is a selenotransferase activity
catalytic activity, acting on a tRNA
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Synonyms
  • "O-phospho-L-seryl-tRNA(Sec):L-selenocysteinyl-tRNA synthase" EXACT[ EC:2 ]
    "O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase" EXACT [] {comment="EC:2.9.1.2"}
    "phosphoseryl-selenocysteinyl-tRNA selenium transferase activity" EXACT
    "SepSecS" EXACT
Secondary IDs
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EC:2.9.1.2
Reactome:R-HSA-2408555 "Sep-tRNA(Sec) is converted to Sec-tRNA(Sec) by PXLP-K284-SEPSECS tetramer"
RHEA:25041