FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term deubiquitinase activity ID (Ontology) GO:0101005 (Gene Ontology)
Definition An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.[ PubMed:30783221 ]
Also Known As "ubiquitinyl hydrolase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Gene Groups Genes
 deubiquitinase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | deubiquitinase activity       --
 NOT | enables | deubiquitinase activity       --
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Vocabulary search: maintenance
  peptidase activity
   |__ubiquitin-like protein peptidase activity
       |__deubiquitinase activity  58 rec.
           |__cysteine-type deubiquitinase activity 46 rec.
           |   |__Met1-linked polyubiquitin deubiquitinase activity 1 rec.
           |__histone deubiquitinase activity
           |   |__histone H2A deubiquitinase activity
           |   |__histone H2B deubiquitinase activity(+)
           |__K11-linked deubiquitinase activity
           |__K48-linked deubiquitinase activity 7 rec.
           |__K63-linked deubiquitinase activity 7 rec.
           |__metal-dependent deubiquitinase activity 7 rec.
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Is a ubiquitin-like protein peptidase activity
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Synonyms
  • "ubiquitinyl hydrolase activity" EXACT
Secondary IDs
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Reactome:R-HSA-9674127 "USP30 deubiquitinates ATM dimer:Ub-p-PEX5"
Reactome:R-HSA-9929353 "Deubiquitination of CD274"