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| Term | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity | ID (Ontology) | GO:0102158 (Gene Ontology) | |||||||
| Definition | Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA. This reaction is the third (dehydration) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit.[ PubMed:16564093 PubMed:19763486 ] | |||||||||
| Also Known As | "very-long-chain 3-hydroxyacyl-CoA dehydratase activity" | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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3-hydroxyacyl-CoA dehydratase activity |__(2E)-enoyl-CoA hydratase activity |__very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity 2 rec. |
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| Is a | (2E)-enoyl-CoA hydratase activity | ||
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External Crossreferences & Linkouts
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EC:4.2.1.134 MetaCyc:RXN-11750 RHEA:39199 RHEA:39211 RHEA:39223 RHEA:39235 RHEA:39271 RHEA:45812 RHEA:79187 RHEA:83119 RHEA:84379 |
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