FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term mCRD-mediated mRNA stability complex ID (Ontology) GO:0106002 (Gene Ontology)
Definition A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP.[ PubMed:11051545 ]
Also Known As "major coding region determinant of instability-mediated mRNA stability complex" ; "major coding region instability determinant-mediated mRNA stability complex" ; "major coding region instability determinant-poly(A)-bridging complex" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 mCRD-mediated mRNA stability complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | mCRD-mediated mRNA stability complex
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cellular_component
 |__protein-containing complex__
cytoplasm                       |
 |__cytosol_____________________|
cellular anatomical structure   |
 |__cytosol_____________________|
                                mCRD-mediated mRNA stability complex  1 rec.
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Is a protein-containing complex
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Synonyms
  • "major coding region determinant of instability-mediated mRNA stability complex" EXACT
    "major coding region instability determinant-mediated mRNA stability complex" EXACT
    "major coding region instability determinant-poly(A)-bridging complex" EXACT
    "major coding-region determinant of instability - poly(A) tail-bridging complex" EXACT
    "mCRD-poly(A)-bridging complex" EXACT
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