FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term peptidyl-lysine 3-dioxygenase activity ID (Ontology) GO:0106155 (Gene Ontology)
Definition Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2.[ PubMed:29915238 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 peptidyl-lysine 3-dioxygenase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | peptidyl-lysine 3-dioxygenase activity       1
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catalytic activity
 |__catalytic activity, acting on a protein____________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen  |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
dioxygenase activity                                                                                   |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
                                                                                         peptidyl-lysine 3-dioxygenase activity  1 rec.
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Is a 2-oxoglutarate-dependent dioxygenase activity
catalytic activity, acting on a protein
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Synonyms
Secondary IDs
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EC:1.14.11.63
Reactome:R-HSA-9629578 "JMJD7 dimer hydroxlates a lysine residue of DRG2"
Reactome:R-HSA-9629591 "JMJD7 dimer hydroxlates a lysine residue of DRG1"
RHEA:57152