FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

peptidyl-lysine 4-dioxygenase activity

ID (Ontology)

GO:0106156 (Gene Ontology)

Definition

Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.[ PubMed:24486019 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
peptidyl-lysine 4-dioxygenase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| peptidyl-lysine 4-dioxygenase activity

Spanning Tree (Parents/Children)

catalytic activity
 |__catalytic activity, acting on a protein____________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen  |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
dioxygenase activity                                                                                   |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
                                                                                         peptidyl-lysine 4-dioxygenase activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	2-oxoglutarate-dependent dioxygenase activity catalytic activity, acting on a protein
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-9629946 "JMJD4:Fe2+ hydroxylates a lysine residue of ETF1" RHEA:57156