FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term GO:0106435 ID (Ontology) GO:0106435 (Gene Ontology)
Definition Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H+.
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      25
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 Gene Groups Genes
 GO:0106435 (all annotations which use CV term, excluding "NOT" statements)       1     25
     enables | GO:0106435       --      25
Spanning Tree (Parents/Children)
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GO:0016788
 |__GO:0052689__
                GO:0106435  26 rec.
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Is a carboxylic ester hydrolase activity
Part of
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Synonyms
  • "ali-esterase activity" RELATED[ EC:3 ]
    "alpha-carboxylesterase activity" NARROW
    "B-esterase activity" NARROW[ EC:3 ]
    "cocaine esterase" NARROW[ EC:3 ]
    "nonspecific carboxylesterase activity" RELATED
    "procaine esterase" NARROW [] {comment="EC:3.1.1.1"}
    "serine esterase activity" NARROW
    "triacetin esterase" NARROW
    "vitamin A esterase" NARROW
Secondary IDs
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EC:3.1.1.1
MetaCyc:CARBOXYLESTERASE-RXN
Reactome:R-HSA-9619024 "CES1 trimer hydrolyses ACEI pro-drugs to ACEIs"
Reactome:R-HSA-9727567 "CES1 hydrolyses sacubitril to sacubitrilat"
Reactome:R-HSA-9749647 "CES2 hydrolyzes ASA-"
RHEA:21164
RHEA:31779
RHEA:38555
RHEA:47348
RHEA:47352
RHEA:47356
RHEA:47360
RHEA:47364
RHEA:47388
RHEA:47392
RHEA:50136
RHEA:50144
RHEA:50148
RHEA:59388
RHEA:63052