FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term phospholipid transfer activity ID (Ontology) GO:0120014 (Gene Ontology)
Definition Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.[ PubMed:20823909 PubMed:24220498 PubMed:25797198 ]
Also Known As "phospholipid carrier activity"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 phospholipid transfer activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     enables | phospholipid transfer activity       --       2
Spanning Tree (Parents/Children)
Only view relationship: 
transporter activity____
lipid carrier activity__|
                        lipid transfer activity
                         |__phospholipid transfer activity  10 rec.
                             |__ceramide 1-phosphate transfer activity
                             |__phosphatidic acid transfer activity 5 rec.
                             |__phosphatidylcholine transfer activity 1 rec.
                             |__phosphatidylethanolamine transfer activity
                             |__phosphatidylglycerol transfer activity
                             |__phosphatidylinositol-4-phosphate-cholesterol exchange activity
                             |__phosphatidylserine transfer activity 2 rec.
                             |   |__phosphatidylserine-phosphatidylinositol-4-phosphate exchange activity 1 rec.
                             |__sphingomyelin transfer activity
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Is a lipid transfer activity
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Synonyms
  • "intermembrane phospholipid transfer activity" NARROW
    "phospholipid carrier activity" EXACT
Secondary IDs
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Reactome:R-HSA-216757 "4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane"
Reactome:R-HSA-382553 "ABCA7:Apo1A-mediated phospholipid efflux"
Reactome:R-HSA-5678706 "ABCB4 transports PC from plasma membrane to extracellular region"
Reactome:R-HSA-5678749 "Defective ABCB4 does not transport PC from plasma membrane to extracellular region"
Reactome:R-HSA-8857662 "ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane"
Reactome:R-HSA-8865637 "MFSD2A transports LPC from extracellular region to plasma membrane"
Reactome:R-HSA-8867876 "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane"