FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term cholesterol transfer activity ID (Ontology) GO:0120020 (Gene Ontology)
Definition Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.[ PubMed:20823909 PubMed:24220498 PubMed:25797198 ]
Also Known As "cholesterol carrier activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Full annotation statements 
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 Genes
 cholesterol transfer activity (all annotations which use CV term, excluding "NOT" statements)
     contributes_to | cholesterol transfer activity
     enables | cholesterol transfer activity
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Vocabulary search: maintenance 
  lipid transfer activity
   |__sterol transfer activity
       |__cholesterol transfer activity  4 rec.
           |__phosphatidylinositol-4-phosphate-cholesterol exchange activity
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Is a sterol transfer activity
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Synonyms
  • "cholesterol carrier activity" EXACT
    "cholesterol transporter activity" BROAD
    "intermembrane cholesterol transfer activity" NARROW
Secondary IDs
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Reactome:R-HSA-1454928 "ABCG4 may mediate cholesterol efflux"
Reactome:R-HSA-216723 "4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane"
Reactome:R-HSA-265443 "NPC1L1-mediated cholesterol uptake"
Reactome:R-HSA-265545 "NPC1L1-mediated phytosterol uptake"
Reactome:R-HSA-266082 "ABCG1-mediated transport of intracellular cholesterol to the cell surface"
Reactome:R-HSA-5682111 "Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane"
Reactome:R-HSA-8951850 "TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane"